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The NADH produced from glycolysis cannot pass through the mitochondrial membrane

ID: 1003128 • Letter: T

Question

The NADH produced from glycolysis cannot pass through the mitochondrial membrane. Therefore, the hydrogen ions and electrons from the NADH in the cytosol are transferred to compounds called___s, which can move in and out of the mitochondria. In the__, malate dehydrogenase catalyzes the reaction of__and NADH to yield___and NAD+. Then a__binds the___and carries it across the___into the____, where___oxidizes___back to___. The oxidation provides hydrogen ions and electrons that are used to reduce___, which can now enter electron transport to synthesize ATP.

Explanation / Answer

The NADH produced from glycolysis cannot pass through the mitochondrial membrane. Therefore the hydrogen ions and electrons from NADH in the cytosol are transferred to compound called (oxaloacetate)s, which can move in and out of mitochondria.

In the (cytosol), malate dehydrogenase catalyzes the reaction of (oxaloacetate) and NaDH to yield (malate) and NAD+.

Then a (transporter) binds the (malate) and carries it across the (mitochondrial membrane) into the (matrix), where (NAD+) oxidizes (malate) back to (oxaloacetate).

The oxidation provides hydrogen ion and electrons that are used to reduce (NAD+) to (NADH), which can now enter electron transport to synthesize ATP.