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Pathophysiology: A woman in her mid-forties complains of “heavy periods that are

ID: 100734 • Letter: P

Question

Pathophysiology:

A woman in her mid-forties complains of “heavy periods that are painful.” She states that for the past 6 months, her periods have become longer in duration. She was alarmed this past month on day 2 and 3 of her period, as she passed several clots and experienced a flow/discharge that was unusually heavy for her. She does have a family history of fibroids and on occasion takes a naproxen for the pain, which she finds does help somewhat. What pathophysiologic concepts do you think apply to this woman’s situation?

Explanation / Answer

Answer:

A woman in her midforties, having heavy and painful periods with several clots may have two pathophysiological concepts:

1. Perimenopause.

2. Uterine fibroids

These concepts are as follows:

1. Perimenopause:

2. Uterine fibroids:

Thus, in this woman, both these pathophysiological concepts may happen together as the heavy and painful periods with several clots accompany the woman with uterine fibroids when she transits into menopause.