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If an inhibitor that blocked the oxidation of NADH was added to a strict aerobe

ID: 101543 • Letter: I

Question

If an inhibitor that blocked the oxidation of NADH was added to a strict aerobe bacterial culture, which two statements would be correct? fermentation would begin and allow for oxidation of NADH ATP energy created by oxidative phosphorylation through respiration would cease adding extra oxygen to the culture could overcome the effects of the inhibitor an acidic waste product would begin to build up in the culture glycolysis and TCA cycle would eventually cease running due to lack of electron acceptors NAD+ would begin to build up in the cell

Explanation / Answer

Let’s check all the statements,

Fermentation would begin and allow for oxidation of NADH- This statement is false because the bacteria is strict aerobe.

ATP energy created by oxidative phosphorylation through respiration would cease- This statement is true but not exactly because inhibition of NADH will reduces the oxidative phosphorylation but FADH2 is there to perform oxidative phosphorylation but not upto the organisms ATP requirements.

Adding extra oxygen to the culture could overcome the effect of the inhibitor- This statement is false, there is no impact of oxygen on the inhibitor.

An acidic waste product would begin to build up in the culture- This statement is false because NADH accumulation will reduce the metabolic rates in the cell.

Glycolysis and TCA cycle would eventually cease running due to lack of electron acceptors- This statement is true because NADH accumulation will reduce the metabolic reaction rates.

NAD+ would begin to build up in cell- This statement is false.