Map A Supercoiling is an important property of DNA tertiary structure that affec
ID: 1028718 • Letter: M
Question
Map A Supercoiling is an important property of DNA tertiary structure that affects essential processes such as replication and transcription How do cells maintain DNA in a negatively supercoiled state? O O Only protein free closed-circle DNA molecules are able to maintain a negatively supercoiled state. DNA molecules can only maintain a negatively supercoiled state if they are single stranded. To maintain a negatively supercoiled state, the DNA molecule needs to either be a closed circle or if linear, constrained at both ends by proteins. Only nicked, circular molecules of DNA can maintain a negatively supercoiled state. Only linear molecules of DNA can maintain a negatively supercoiled state. O Which structural changes become more favorable when a DNA molecule is negatively supercoiled? DNA triple helix formation cruciform formation formation of Z-form DNA formation of A-form DNA Strand separationExplanation / Answer
how do cells maintain DNA in a negatively supercoiled state ?
Ans.-Only nicked, circular molecules of DNA can maintain a negetively spercoiled state.
Which structural changes become more favorable when a DNA molecule is negatively spercoiled?
Ans. - formation of Z-form DNA and Strand separation.