Regulated Activation Of Cell-Membrane Receptors By Metal-Chelating Agonists\" Pe
ID: 1029217 • Letter: R
Question
Regulated Activation Of Cell-Membrane Receptors By Metal-Chelating Agonists" Peter I. Lamb; Shin Shay C Tian;Evelyn O Delorme:Juan I. Luengo; Kevin J. Duffy Smithkline Beecham Corporation; Ligand Pharmaceuticals Inc). 2-Bromo-6-substitutedphenol 2-Bromophenol (34.6 g, XX mol) was added slowly to a cold ( 10°C) solution of sodium nitrate (30.5 g. XX mol) in conc sulfuric acid (42 g) and water (74 mL) and the resulting mixtüre was allowed to stir at room temperature for 2h. Water (210 mL) was added and the resulting mixture was extracted with diethyl ether and the extract was dried (MgS04), filtered and concentrated. The residue was purified by flash chromatography (silica gel, 10 percent ethyl acetate/hexanes) to afford first the title compound (XX g: 25 percent) as a bright, yellow solid. NMR (300 MHz. CDCL) 11.10 (S, 1 H), 8.13 (d, J-7.9 Hz. 1H), 7.89 (6, J-7.9 Hz, 1H), 6.90 (t, J-7.9 Hz, IH). 1) (4 points) Draw the overall reaction scheme for the reaction descried above. (4 points) What tvne of ranatian .Explanation / Answer
8. is Right and it's formula will be MgSO4.7 H2O
Reaction:
MgSO4 + 7 H2O ------------->MgSO4. 7H2O
9.MgSO4 is a hygroscopic substance that absorbs water , NaOH also absorb water ,but itself get dissolve into it.So,NaOH can be used accordingly by keeping this in mind.