Please explain The biologically active turmeric isolate curcurmin (1) is under d

Question

Please explain

The biologically active turmeric isolate curcurmin (1) is under development as an anti-cancer chemotherapeutic agent Recent mechanism-of-action studies have identified one potential target the nuclear exporter protein CRM1. Curcumin inhibits nuclear trafficking by this protein, an activity that is speculated to underlie the promising anticancer and anti-inflammatory activity of 1. In fact, these studies suggest that curcumin forms a covalent linkage to ore particular amino acid sidechain of CRM 1 as the basis for its inhibitory activity Which amino acid is likely involved? Select one: a.a b.b c.c d.d

Explanation / Answer

Curcumrin has been seen to form covalent linkage with one of the amino acid

The amino acid with which curcumrin forms this linkage would be,

b. b

Cysteine is the amino acid with which the compound forms covalent linkage.

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