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Physician orders antibiotic amoxicillin 150 mg q8h for 7 days for a 5 year old p

ID: 125042 • Letter: P

Question

Physician orders antibiotic amoxicillin 150 mg q8h for 7 days for a 5 year old patient weighing 33 lb. Recommended dosage is 20-40 mg/kg/day divided in 3 equal doses. Pharmacy stock is:

AMOXIL 250 mg/5 mL

100 mL (when reconstituted)

What is the safe daily dose range for this medication?

What is the safe single dose range for this medication?

Is the doctor's order safe?

Based on the doctor's order, how many mL of medication will you administer per dose for this patient?

How many individual doses are available in this bottle of medication given by the pharmacy?

Explanation / Answer

Order = 150 mg Q8h X 7 days

Safe daily dose range for this medicine is = 20-40mg/kg

convert weight into KG

1 pound = 0.45 Kg

33 pounds = 14.85 Kg

Safe minimum dose is 20mg /kg = 20x 14.85= 297 mg per day

Safe maximum dose is 40mg/kg = 40 X 14.85= 594 mg per day

Safe dose range is 297 mg - 594 mg per day divided in three equla doses

Minimum Safe single dose range = 297/3 =99mg

Maximum  Safe single dose range = 594/3= 198mg

Safe single dose range is 99mg-198mg

Doctors order is 150mg q8h which is coming in between safe range.. So It is correct order

Dose to be administered as per order = amt ordered / amt available X strength

= 150/250 x 5= 3 ml

pottle is of 100ml and each dose is 3 ml

total available doses = 100/3= approx 33 single doses