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Part A Describe two pieces of evidence supporting the idea that angiogenesis is

ID: 132145 • Letter: P

Question

Part A Describe two pieces of evidence supporting the idea that angiogenesis is required for tumors to grow beyond a tiny clump of cells. Drag the terms on the left to the appropriate blanks on the right to complete the sentences. Reset Help fail to link up to remain alive and become infiltrated with 1-2 mm in diameter die before they Cancer cells injected into an isolated rabbit thyroid gland kept alive with a nutrient solution the organ's blood vessels, the tumors grow to When injected into live animals, the same tumors blood vessels and grow to Cancer cells placed in the anterior chamber of a rabbit's eye, where there are no blood vessels, reach In contrast, cancer cells placed directly on the iris blood vessels and the tumors grow to enormous size

Explanation / Answer

Cancer cell injected into an isloated rabbit thyroid gland kept alive with a nutrient solution fail to link up to the organ's blood vessels, the tumours grow to 1-2 mm in diameter. When injected into live animals, the same tumors become infiltrated with blood vessels and grow to enormous size.

Cancer cells placed in the anterior chamber of rabbit's eye, where there are o blood vessels, die before they reach enormous size. In cotrast, cancer cells placed on the iris become infiltrated with blood vessels and the tumors grow to 1-2 mm in diameter.