For the following three questions, consider the DNA sequence below. Note only on
ID: 147178 • Letter: F
Question
For the following three questions, consider the DNA sequence below. Note only one strand of the double helix is given. 5-ACTGGCATC-3 34) What is the sequence of the other strand of the double helix? A) 5. _ T G A C C G T A G-3, B) 5 -GATGCCAGT-3 C) 5'-CTACGGTCA-3 D) 5'-ACTGGCATC-3 E) 5'-ACUGGCAUC-3 35) How many phosphodiester bonds are in the double helix? (Hint: Consider both strands) 36) How many hydrogen bonds are in the double helix? 37) Which of the following best represents the Central Dogma of Molecular Biology? A) 18 B) 20 C) 23 D) 8 E) 16 A) 8 B) 23 C) 18 D) 27 E) 16 A) RNA- protein DNA B) RNA DNA-protein C) protein DNA RNA D) DNA RNA-protein E) DNA protein-RNAExplanation / Answer
Ans) From Chargaff rule, we know that Adenine (A) always bind with Thymine(T) with 2 hydrogen bond and Guanine (G) binds with Cytosine (C) with 3 hydrogen bond.
34)
The given sequence of the DNA is:-
5' ACTGGCATC 3'
the sequence of the otyher strand of the DNA is 3' TGACCGTAG 5'
So, the option will be A) 3' TGACCGTAG 5'
35) The phosphodiester bond is present in between two nucleotide. The number of phosphodiester bond present in 3' TGACCGTAG 5' sequence is 8. So, the double helix will have 16 phosphodiester bond. So. answer will be E) 16.
36) The total number of nucleotide present in a sequence of double helix is 9. We know Adenine (A) always bind with Thymine(T) with 2 hydrogen bond and Guanine (G) binds with Cytosine (C) with 3 hydrogen bond.. Here the number of A-T and G-C linkages are 4 and 5 respectively. So, the number of hydrogen bond is (4 X 2 ) + (5 X 3) = 8 + 15 = 23 hydrogen bond.
The option will be B) 23
Ans 37) The central dogma of molecular biology is DNA -> RNA -> Protein, It describe two steps process that is transcription and translation. The DNA is converted through the process of transcription into RNA and this RNA is translated in protein. This is flow of the genes to form protein.
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