Constants 1 Perodic Table -Part A Properties of some amino acids found in protei

Question

Constants 1 Perodic Table -Part A Properties of some amino acids found in proteins Name and 3-leter If you sketch the titration curve for a-meanotropin (Ser-Tyr-Ser-Met Glu-His-Phe-Ars-Trp-Gly Lys-Pro-Val), near what pli values would you expect the curve to exhibit inflections? Assume the pi,s of the N- and C-ermini ane 7.9 and 3.8, respectvely For side chains, assume the pha values gven Side Chain 12.5 Arginine R, Arg Asparbe D, Asp Match the iteres in the left column to the appropriate blanks in the santence on the right. 3.9 Cysteine C, Cys Gluiamic g, Glu Hisidine H, His Lysine K, Lys Tyrosine Y, Tyr 4.2 The curve wit exhibt inflections comesponding to groupisi verating near 4 f 6.0 groupls) near 6.5 groupls) near 10 group/s) near 8 ( groups) two carboxyl terminus and glutamie side chain 10.1 near 12 Apphuximate values found for side chains on the ree amino acids. WP. Jencks and J Regenstein (1976) lonization constants of acids and based in Handbook of Biochemislry and Molecular Biolegy, 3rd ad G. Fasman (ed) CRC Press, Boca Raton FL histidine tyrosine arginine glutamic side chain ysine carboxyl terminus N terminus eystein aspartic side chain lysine and tyrosine

Explanation / Answer

The curve will exhibit infections corresponding to two groups titrating near 4 (carboxyl terminus and glutamic side chain) one group near 6.5 (histidine), two groups near 8 (N-terminus and lysine), one group near 10 (tyrosine) and one group near 12 (arginine).

Related Questions

Navigate

• Browse (All)
• Browse C
• Subjects

---