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Mice from wild populations typically have gray-brown (or agouti) fur, but in one

ID: 150456 • Letter: M

Question

Mice from wild populations typically have gray-brown (or agouti) fur, but in one laboratory strain, some of the mice have off-white fur. A single off-white male is mated to several agouti females and 40 progeny are produced; 22 with agouti fur and 18 with off-white fur. The Fi agouti animals are then intercrossed with each other to produce an F2 generation, all of which are agouti. Similarly, the Fi off-white animals are intercrossed with each other, but their F2 progeny segregate into two classes; 18 are agouti, and 52 are off-white. Subsequent crosses between off-white F2 animals also segregate off-white and agouti progeny. (For symbols, use a letter that represents the dominant phenotype, uppercase for dominant, lowercase for recessive.) 4.

Explanation / Answer

White = Aa X aa Agouti

Agouti aa 22 : White Aa 18

Inter Cross F1 white     Aa X Aa

                                  AA    Aa   Aa - White

                                   aa - agouti

Inter cross F1 Agouti    aa X aa

                       All are agouti aa

A a a Aa white aa agouti a Aa white aa agouti