Academic Integrity: tutoring, explanations, and feedback — we don’t complete graded work or submit on a student’s behalf.

I havea question that has to do with the autonomic nervous system. It\'sabout ho

ID: 1631 • Letter: I

Question

I havea question that has to do with the autonomic nervous system. It'sabout how side effects arise from the use of anti-cholinergicganglion blocking drugs, as well as anti-muscarinic drugs. Iunderstand that nicotinic and muscarinic receptors are located onthe autonomic ganglion. A fast EPSP occurs when acetylcholine bindswith the nicotinic receptor, but a slow EPSP occurs when it bindswith the muscarinic receptor on the ganglion. These receptors arealso located on the effector organs which synapse with thepostganglionic fibers. But I don't fully understand the concept ofwhat all of this has to do with causing side effects to occur. Forinstance, an anti-muscarinic drug is given for excessgastrointestinal motility, but it also may impair cognition. Howcome?

Explanation / Answer

help?