Identify each of the following statements as TRUE or FALSE (remember to provider
ID: 163245 • Letter: I
Question
Identify each of the following statements as TRUE or FALSE (remember to providereasoning to justify your answer).
i. If a pair of loci exhibits significant linkage disequilibrium, those loci must be
physically linked on the same chromosome.
ii. Each of us received half of our mitochondrial DNA from our mom and halffrom our dad, but the paternally inherited alleles are always recessive, so thematernal contribution determines the phenotype.
iii. For populations in which individuals preferentially mate with their closerelatives, there will tend to be an excess of homozygous individuals relative tothe expectations of Hardy-Weinberg equilibrium.
Explanation / Answer
1. True
linkage disequilibrium when the frequency of association of their different alleles is higher or lower than what would be expected if the loci were independent and associated randomly.
2. False
Unlike nuclear DNA, which comes from both parents, mitochondrial DNA comes only from the mother.
3.True
If two siblings have a child, then that child only has two rather than the normal four grandparents. In these circumstances the probability of heterozygosity will reduced and excess of homozygous individuals will be there.