Describe one experiment that supports the statement that an rRNA and not a prote
ID: 163743 • Letter: D
Question
Describe one experiment that supports the statement that an rRNA and not a protein component of the ribosome catalyzes the peptidyl transferase reaction.
Drag the terms on the left to the appropriate blanks on the right to complete the sentences.
The simplest experiment is to treat _________ with _________ and ask if the resulting ribosome can still synthesize _________. After such a treatment, it was found that, even after most of the protein was removed, __________ formation could still occur. Structural studies further supported that _________ could catalyze peptide bond formation because no _________ is present within 18 angstrom of the active site.
amino acid
peptide bond
a protease
the ribosome
new protein
the RNA
Explanation / Answer
The simplest experiment is to treat with peptide bond with a protease and ask if the resulting ribosomes can still synthesize new protein. After such a treatment, it was found that, even after most of the protein was removed the RNA formation could still occour. Structural studies further supported that the ribosome could catalyze peptide bond formation because no amino acid is present with in 18 angastrom of the activevsite.