Please explain the answer and show the answer clear. Thank you. Amino Acid Seque

Question

Please explain the answer and show the answer clear. Thank you.

Amino Acid Sequence and Protein Structure our growing understanding of how proteins fold allows researchers to make predictions about protein structure based on primary amino acid sequence data. Ile-Ala-His-Thr-Tyr-Gly-Pro-Phe-Glu-Ala-Ala-Met Cys-Lys-Trp-Glu-Ala-Gln-Pro-Asp-Gly-Met-Glu-Cys-Ala-Phe-His-Arg. (a) In the amino acid sequence above, where would you predict that bends or B turns would occur? (b) Where might intrachain disulfide cross-linkage be formed? (c) Assuming that this sequence is part of a larger globular protein, indicate the probable location (the external surface or interior of the protein) of the following amino acid residues: Asp, Ile, Thr, Ala, Gln, Lys. Explain your reasoning.

Explanation / Answer

a) Ile-Ala-His-Thr-Tyr-Gly-Pro-Phe-Glu-Ala-Ala-Met-Cys-Lys-Trp-Glu-Ala-Gln-Pro-Asp-Gly-Met-Glu-Cys-Ala-Phe-His-Arg

b) Intrachain disulfide cross linkage occur between Cys residues. It occur at position 13 and position 24

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