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Most neurons express multiple types of K+ currents, some of which are gated by v

ID: 169791 • Letter: M

Question

Most neurons express multiple types of K+ currents, some of which are gated by voltage and others by Ca2+, and these currents contribute to action potential repolarization and to repetitive firing.

a. What would you predict would be the effect on the action potential of blocking all K+ currents? You may wish to provide a sketch (in lieu of a written reply) to illustrate your answer.

b. What would you predict would be the effect on the action potential of increasing the densities of K+ channels twofold? You may wish to provide a sketch/written reply to illustrate your answer.

Explanation / Answer

A) blocking of K+ ion channel will result in increased duration of action potential, as Na+ ion channel will be active resulting in the outward flow of sodum ion making inside neagative resulting in the depolarisation of longer time.