Loss of BRCA activity contributes to cancer because Without BRCA, DNA polymerase
ID: 175104 • Letter: L
Question
Loss of BRCA activity contributes to cancer because
Without BRCA, DNA polymerase can't use its proof-reading activity
Without BRCA, cells cannot perform homology directed repair of double-stranded breaks
Without BRCA, DNA damage-sensing kinases cannot establish a cell cycle checkpoint
Without BRCA, cells can't remove oxidized bases
A.Without BRCA, DNA polymerase can't use its proof-reading activity
B.Without BRCA, cells cannot perform homology directed repair of double-stranded breaks
C.Without BRCA, DNA damage-sensing kinases cannot establish a cell cycle checkpoint
D.Without BRCA, cells can't remove oxidized bases
Explanation / Answer
Without BRCA, cell cannot perform homology directed repair of double stranded break.
Note- BRCA normally expressed in cell of breast and other tissue where ther help repair damaged DNA or destroy cell if DNA cannot be repaired.