In Drosophila the genes twist, snail, rhomboid and sog are expressed at differin

Question

In Drosophila the genes twist, snail, rhomboid and sog are expressed at differing positions along the dorsal-ventral (DV) body axis. Which of the following does not contribute to this phenomenon?

a. These four genes have Dorsal-binding sites of differing chemical affinity. b. Dorsal protein can activate the transcription of all four genes. c. Within its nuclei, the embryo has a ventral-to-dorsal (high-to-low) concentration gradient of Dorsal protein. d. The Snail protein represses transcription of rhomboid and sog in ventral tissues. e. When activated, the Toll receptor signal transduction pathway phosphorylates the Dorsal protein.

Explanation / Answer

The correct answer is "e".

Toll binds to spazle which phosphorylates cactus; not Dorsal. This disrupts the binding between cactus protein and Dorsal protein. Now, dorsal protein can enter nucleus.

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