Can someone let me know if I am correct please.... Help ASAP Question 1 Ion chan
ID: 175832 • Letter: C
Question
Can someone let me know if I am correct please.... Help ASAP
Question 1
Ion channels
detect changes in membrane potential that trigger their opening and closing
mediate the movement of ions against their concentration gradient across the plasma membrane
contain gating regions formed by hydrophobic amino acids
are formed by peripheral membrane proteins
usually require energy in the form of ATP hydrolysis to function
1 points
Question 2
TNF-alpha receptor is an important cellular receptor involved in the activation of the extracellular apoptotic pathway. This integral plasma membrane protein is likely synthesized
in Golgi-associated ribosomes
in ribosomes associated to the plasma membrane
in ribosomes associated to the inner nuclear membrane
in free-standing ribosomes in the cytoplasm of the cell
in ribosomes associated to the plasma membrane
1 points
Question 3
Nucleocytoplasmic traffic
is not regulated
is regulated by a gradient in the concentration of a GTPase protein known as Ran
stops completely during S phase
determines the developmental fate of a cell, including the initiation of apoptosis
is increased during mitosis
1 points
Question 4
In mammalian cells, chromosomes are
linear molecules of double stranded DNA
circular molecules of double stranded DNA
linear molecules of single stranded DNA
circular molecules of single stranded DNA
1 points
Question 5
In mammalian cells, DNA replication
occurs in the nucleus
is required for progression into G1 phase
occurs twice per cell cycle to maintain the 2n chromosomal number
requires nuclear envelope disassembly
takes place throughout the entire cell cycle
1 points
Question 6
TIMP-1 is a GPI anchored protein. TIMP-1 is likely to be located
in the plasma membrane, facing the extracellular environment
in the Golgi, facing the lumen of the Golgi
in the plasma membrane, facing the cytoplasm
in the ER membrane, facing the lumen of the ER
along the secretory pathway, alternating its orientation to both sides of the membranes of the secretory pathway
1 points
Question 7
PCNA and DNA Polymerase delta are synthesized during the G1 stage of the cell cycle. This is important because
it ensures that mitosis will only take place when the DNA has already been replicated in full
it provides for an additional mechanism to restrict DNA replication to S phase
it prevents DNA replication in the absence of phosphorylated MCM
it prevents uncontrolled gene transcription during S phase
it keeps the DNA from being replicated in the presence of DNA damage
1 points
Question 8
The nucleus
disassembles and ceases to exist upon phosphorylation of the lamins
is a homogeneous environment in which all nuclear components are equally distributed throughout
is connected with the cell surface by pore forming proteins
is functionally equivalent to mitochondria
contains a nucleoplasm whose ionic composition is substantially different from that of the cytoplasm
1 points
Question 9
The 5' cap
is added by a ribozyme
allows the binding of mRNAs to the translocon therefore allowing the synthesis of membrane-bound proteins
is always a methionine residue
protects the 3’ end of mRNAs
is important for mRNA translation
1 points
Question 10
These are proteins known to accumulate during specific stages of the cell cycle, leading to the activation of specific kinases that in turn phosphorylate specific substrates
Cdcs
Caspases
Cdks
Cyclins
Cyclokinases
a.detect changes in membrane potential that trigger their opening and closing
b.mediate the movement of ions against their concentration gradient across the plasma membrane
c.contain gating regions formed by hydrophobic amino acids
d.are formed by peripheral membrane proteins
e.usually require energy in the form of ATP hydrolysis to function
Explanation / Answer
1) option B is the correct answer. Ion channels forms pore in the membrane and helps in establishing membrane potential by gating the flow of ions across the cell membrane.
2.) Option E is the correct answer. Cytokinesis are formed in ribosomes bind to endoplasmic reticulum. TNF receptor binds to the ribosomes bind to plasma membrane.