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Can someone let me know if I am correct please.... Help ASAP Question 1 Ion chan

ID: 175832 • Letter: C

Question

Can someone let me know if I am correct please.... Help ASAP

Question 1

Ion channels

detect changes in membrane potential that trigger their opening and closing

mediate the movement of ions against their concentration gradient across the plasma membrane

contain gating regions formed by hydrophobic amino acids

are formed by peripheral membrane proteins

usually require energy in the form of ATP hydrolysis to function

1 points

Question 2

TNF-alpha receptor is an important cellular receptor involved in the activation of the extracellular apoptotic pathway. This integral plasma membrane protein is likely synthesized

in Golgi-associated ribosomes

in ribosomes associated to the plasma membrane

in ribosomes associated to the inner nuclear membrane

in free-standing ribosomes in the cytoplasm of the cell

in ribosomes associated to the plasma membrane

1 points

Question 3

Nucleocytoplasmic traffic

is not regulated

is regulated by a gradient in the concentration of a GTPase protein known as Ran

stops completely during S phase

determines the developmental fate of a cell, including the initiation of apoptosis

is increased during mitosis

1 points

Question 4

In mammalian cells, chromosomes are

linear molecules of double stranded DNA

circular molecules of double stranded DNA

linear molecules of single stranded DNA

circular molecules of single stranded DNA

1 points

Question 5

In mammalian cells, DNA replication

occurs in the nucleus

is required for progression into G1 phase

occurs twice per cell cycle to maintain the 2n chromosomal number

requires nuclear envelope disassembly

takes place throughout the entire cell cycle

1 points

Question 6

TIMP-1 is a GPI anchored protein. TIMP-1 is likely to be located

in the plasma membrane, facing the extracellular environment

in the Golgi, facing the lumen of the Golgi

in the plasma membrane, facing the cytoplasm

in the ER membrane, facing the lumen of the ER

along the secretory pathway, alternating its orientation to both sides of the membranes of the secretory pathway

1 points

Question 7

PCNA and DNA Polymerase delta are synthesized during the G1 stage of the cell cycle. This is important because

it ensures that mitosis will only take place when the DNA has already been replicated in full

it provides for an additional mechanism to restrict DNA replication to S phase

it prevents DNA replication in the absence of phosphorylated MCM

it prevents uncontrolled gene transcription during S phase

it keeps the DNA from being replicated in the presence of DNA damage

1 points

Question 8

The nucleus

disassembles and ceases to exist upon phosphorylation of the lamins

is a homogeneous environment in which all nuclear components are equally distributed throughout

is connected with the cell surface by pore forming proteins

is functionally equivalent to mitochondria

contains a nucleoplasm whose ionic composition is substantially different from that of the cytoplasm

1 points

Question 9

The 5' cap

is added by a ribozyme

allows the binding of mRNAs to the translocon therefore allowing the synthesis of membrane-bound proteins

is always a methionine residue

protects the 3’ end of mRNAs

is important for mRNA translation

1 points

Question 10

These are proteins known to accumulate during specific stages of the cell cycle, leading to the activation of specific kinases that in turn phosphorylate specific substrates

Cdcs

Caspases

Cdks

Cyclins

Cyclokinases

a.

detect changes in membrane potential that trigger their opening and closing

b.

mediate the movement of ions against their concentration gradient across the plasma membrane

c.

contain gating regions formed by hydrophobic amino acids

d.

are formed by peripheral membrane proteins

e.

usually require energy in the form of ATP hydrolysis to function

Explanation / Answer

1) option B is the correct answer. Ion channels forms pore in the membrane and helps in establishing membrane potential by gating the flow of ions across the cell membrane.

2.) Option E is the correct answer. Cytokinesis are formed in ribosomes bind to endoplasmic reticulum. TNF receptor binds to the ribosomes bind to plasma membrane.