Blond Solomon Islanders have a different mutation responsible for their hair col
ID: 179504 • Letter: B
Question
Blond Solomon Islanders have a different mutation responsible for their hair color. The version of the TYRP1 hair color gene (allele) for dark hair has a C at position 277 of the coding sequence of tyrosinase-related protein 1 while the TYRP1 allele for blond hair has a T. People have 2 copies of the TYRP1 gene: one allele from their mother and one allele from their father. Thus three genotypes are expected in the Solomon Islands: CC (each allele has a C at position 277), CT (one allele with C, one with T), and TT (both alleles have T at position 277). Hair color for people of all three genotypes was measured with a spectrometer by collecting hair samples and determining the amount of reflectance of light at a particular wavelength. What level of structure is affected by this mutation (circle all that apply)? Question 8 options: A) primary B) secondary C) tertiary
Explanation / Answer
The mutation in the gene TYRP is denoted as C227T, as this mutation is in the coding region, it will effect the primary structure, secondary structure and teritiary structure. Secondary and teritiary structure is affected becuase of the change in the aminoacid from Cystein which is has -SH to threonine which is an alcohol containing aminoacid.