Why are the values of the free energy changes for the nearest neighbor interacti
ID: 186397 • Letter: W
Question
Why are the values of the free energy changes for the nearest neighbor interactions in the stability matrix always negative? Select one: a. The addition of a basepair to a growing helix leads to an increase in the number of conformational states available to the DNA. b. The addition of a basepair to a growing helix leads to big increase in translational entropy. c. The addition of a basepair to a growing helix leads to an increase in the electrostatic repulsion between the strands. d. The addition of a basepair next to an existing basepair does not change the hydrogen bonding free energy. e. The addition of a basepair to a growing helix results in steric repulsion between adjacently stacked bases. f. The addition of a basepair to a growing helix increases the number of hydrogen bonds. g. The addition of a basepair to a growing helix decreases the number of conformational states available to the DNA. h. The addition of a basepair to a growing helix decreases the entropy of the solvent i. None of the above.Explanation / Answer
The stability matrix is always negetive due to the negetively charged phosphate group present in DNA. Hence the answer is
I. None of the above