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Consider the above pedigree of a cat mating. We are tracking the L locus that de

ID: 186715 • Letter: C

Question

Consider the above pedigree of a cat mating. We are tracking the L locus that determines cat hair length. Allele l is rare and causes long hair. In the pedigree, black indicate cats with long hair, and white indicates cats with short hair. Squares are males. Circles are females. The l allele is rare such that the probability of mating with an outbred carrier (i.e a non-relative) is effectively 0.

What is the mode of inheritance (autosomal dominant, autosomal recessive, X-linked dominant, or X-linked recessive)? Explain how you came to this conclusion by writing the genotypes of each member of the pedigree (either by hand on the pedigree or below)?

Genotypes:

I-1:

I-2:                                                                               III-1:

II-1:                                                                              III-2:

II-2:                                                                              III-3:

II-3:                                                                              III-4:

II-4:                                                                              IV-1:

II-5:

5 4 3 4 2

Explanation / Answer

L is dominant allele and causes short hair.
l is recessive allele and causes long hair.

LL or Ll = Short hair
ll = Long hair

Genotypes:

I-1 = ll
I-2 = Ll
II-1 = LL   
II-2 = Ll   
II-3 = LL   
II-4 = Ll   
II-5 = LL
III-1 = LL
III-2 = Ll
III-3 = Ll
III-4 = LL
IV-1 = ll

Some of the individuals such as III-1 and III-4 can be Ll