4 pts Which of the following statements regarding histone methylation is incorre
ID: 190395 • Letter: 4
Question
4 pts Which of the following statements regarding histone methylation is incorrect? All types of trimethylation (H3K4, H3K27 and H3K79) are associated with transcriptional repression O Different levels of histone methylation (mono, di or trimethylation) can have opposite effects on transcription (activation or repression) The position of the methylated lysine with the histone N-terminal tail G.e K4, K9, K27,K79) influences whether a gene will be activated or repressed. Monormethylation of any histone H3 lysine residue appears to be a purely activating mark or signal .Ne PreviousExplanation / Answer
a. This statement is incorrect because these histones(H3k4, H3k79) are involved in activation.
b. Mono methylation of any lysine of H3 leads to activation signal because methylation is specific event and not a random exercise. Methylation of only specific residues can either activate or repress transcription