Although mutations in the coding region of a genes can lead to changes in protei
ID: 193416 • Letter: A
Question
Although mutations in the coding region of a genes can lead to changes in protein sequence (non-synonomous, nonsense, frameshift) there are plenty of mutations in non-coding regions within the genome that can alter how gene are expressed. In the scenarios below, please indicate what non-coding regions might contain a SNP (Single Nucleotide Polymorphism) mutation, and how this SNP mutation might lead to the given scenario:
a. no transcription occurs for a particular gene
b. Transcription occurs, but the mRNA is shorter than normal (by 100 bp)
c. Transcription occurs, but the mRNA is longer than normal (100 bp longer)
Explanation / Answer
Option c is correct because gene level mutation are more common than cromosomal mutation which is focus on noemal alteration sotranscription occurs,but tje mRNA is longer than normal (100bp longer).