Consider the following metabolic pathway in yeast where V, W, X, Y, Z are the me
ID: 195260 • Letter: C
Question
Consider the following metabolic pathway in yeast where V, W, X, Y, Z are the metabolic intermediates in the pathway. --->V--->W--->X--->Y--->Z A particular mutant yeast does not grow in minimal medium but will grow on minimal medium plus metabolite X, Y or Z but not W. This yeast strain (strain A) is mated with another strain (strain B) with a defective enzyme in the same metabolic pathway as the first strain. This mating results in diploid cells that multiply by mitosis. The diploid yeast cells from this mating grow on minimal medium with no additional nutrients. This is possible because:
A. Both strains have the same defective enzyme
B. The mutant genes are repaired in the diploid cells
C. Both strains have mutations in the same enzyme coding gene but in a different part of the gene
D. Each strain has a mutation at a different enzyme coding gene affecting the pathway
Explanation / Answer
c, Both strains have mutations in the same enzyme coding gene but in a different part of the gene