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Consider this reaction step in glycolysis (it is convenient to abbreviate the lo

ID: 195997 • Letter: C

Question

Consider this reaction step in glycolysis (it is convenient to abbreviate the long chemical name).

fructose-6-phosphate (F6P) + phosphate (Pi) --------> fructose-1, 6-bisphosphate (F1, 6BP)

to abbreviate the long chemical names). Utant + fructose-1,6-bisphosphate (F1,6BP) I. Consider this reaction step in glycolysis (it is convenient to abbreviate fructose-6-phosphate (F6P) + phosphate (Pi) fructose-16 Under standard conditions, an initial 1 M solution (cach) of pyruvat concentrations of species at equilibrium: (F6P]=[Pi] = 0.957 M, (F1,6BPI = A. What is the equilibrium constant, Kogº", of this reaction under sts of pyruvate and Pi react to produce the following 55 M. F1,6BP) = 00.043 M. B. What is the free energy change, AG°', of this reaction under standard conditions C. Is this reaction spontaneous under standard conditions? How can you tell?

Explanation / Answer

Keq= [fructose 1,6 bisphosphate]/[fructose 6 phosphate][Pi]

= 0.043/0.957*0.957

=0.043/0.915

=0.0470

Delta G = Delta G0 +RTlnKeq

At equilibrium Delta G = 0

So Delta G0 = -RTlnKeq

= -8.314 * 298 * 0.0470

= -116.44 KJ

Yes the reaction is spontaneous as the value of delta G is negative.