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Blood Types Human blood types involve three alleles at the same locus: A, B, and

ID: 197575 • Letter: B

Question

Blood Types Human blood types involve three alleles at the same locus: A, B, and O. These alleles produce spec antigens: Allele A produces an A antigen, allele B produces a B antigen, and allele O produces no Alleles A and B are co-dominant, meaning that you will see both antigen A and antigen B in antigens. individuals who are heterozygous AB. Both alleles A and B are completely dominant over allele o. Because of the co-dominant characteristic of the A and B alleles, we have four possible phenotypes: A, B, AB and O. 1. What are the possible blood types of offspring that result when the following cro A) AB X BO made: 2. If the mother is blood type A and the child is blood type O, can the father be blood type B? 3. If the mother is blood type O and the child is blood type A, can the father be blood type B?

Explanation / Answer

Antibodies are the glycoproteins located in plasma, provide protection against the pathogens by eliminating them from the body and antigens are present the cell membrane. Based on the presence and absence of Antibodies in plasma & antigens on RBC membrane, ABO blood group system classifies the blood into four types. In 1900 the ABO system was first identified by the Karl Landsteiner and awarded with Nobel Prize in 1930.

A person with blood Group A has A antigen on RBC and B antibodies in plasma

A person with blood Group B has B antigen on RBC and A antibodies in plasma

A person with blood Group AB has AB antigens on RBC and no antibodies in plasma

A person with blood Group O has no antigens on RBC and   AB antibodies in plasma

1. Possible blood types of offspring

MOTHER                  FATHER                   OFFSPRING

AB                  X         BO                  =          AB/ A/ B/ O

AB                  X         OO                  =          A/ B

B0                   X         AO                  =          AB/ A/ B/ O

2. if the mother is blood type A and the child is blood type O, can the father be blood type B?

Ans) yes it can. If the Mother has blood type A and the father has blood type B then four different combinations (AB/ A/ B/ O) are possible among them baby can acquire O blood type.

3. If the mother is blood type O and the child is blood type A, can the father be blood type B?

Ans) No it is not possible. If the Mother has blood type O and the father has blood type B then baby can get B/O blood type but not the A blood type.