Please clearly answer B and C Question Human Gene Architecture, using HTT as an

Question

Please clearly answer B and C Question Human Gene Architecture, using HTT as an example, 5 points 4: A. 1 point. The HTT gene that we discussed in class has 67 exons, shown as vertical lines and boxes in the diagram below. How many introns does it have?(hint: do not try to count them). HTT ,9021117 NP 0021024 B. 1 point. The HTT gene spans 180,000 bp in the human genome but encodes an mRNA that is only 13,500 bp long. Why is the HTT mRNA so much shorter than its corresponding gene in the genome? C. 3 points. Do you expect the length of an mRNA molecule to always be a multiple of 3? Circle your answer: YES NO Explain in one sentence and provide a diagram of an mRNA labeling the parts we discussed in class.

Explanation / Answer

B. The shorter length of mRNA is due to editing or splicing of genes in nucleus for translation into mRNA which ia process of central dogma.

C: YES. m-RNA codes for proteins which are made up of amino-acids and hence, have to be in triplets code.

Structure of mRNA:-

5' End[CAP REGION][UNTRANSLATED REGION][ CODING SEQUENCE ][ UNTRANSLATED REGION ][POLY A TAIL]3' End

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