Please help with some epigenetics! In addition to Rett Syndrome (RTT), MeCP2 mut
ID: 200328 • Letter: P
Question
Please help with some epigenetics!
In addition to Rett Syndrome (RTT), MeCP2 mutations result in at least 3 other described syndromes.
1. Identify and briefly describe the other syndromes.
2. What are the differences in the outcomes of MeCP2 mutations in males vs. females? Why do you think these are so different? Provide a brief summary of the difference (i.e. a very short comparison of how the syndromes differ between males and females)
3) why might the same mutation give such different syndromes in different genders?
Please explain in detail.
Explanation / Answer
1). The diseases associated with the MeCP2 (methyl-CpG binding protein 2) mutations include,