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Problem 2 (20 points) 11JZ You are performing an experiment measuring the membra

ID: 203318 • Letter: P

Question

Problem 2 (20 points) 11JZ You are performing an experiment measuring the membrane potential of a sne potential expeime of conditions In your first set of experiments, you measure the resting m as you gradually increase the extracellular potassium concentration. Initially in cold seawater (extracellular solution) at 4°C. Then. you perform the sathe following grathe resting temperature seawater at (250c). From these experiments, you generate ih oncentration the notice the direction of the Y-axis- as you increase extracellular potassiu membrane potential is becoming depolarized. under a variety , you perform the concentration the resting 80 25°C -70- 50 50 -40 -30 0 +10 1 2 5 10 20 50 100 200 External Potassium Concentration (mM) ume that as you changed external potassium concentration, you alter tions appropriately such that charge balance and osmotic balan tained plain why changing the concentration of extracellular potassium changes the m tial

Explanation / Answer

More extracellular K+ concentration results in the depolarization as K+ ion movement in the extracellular side decreases (K+ leakage stops) and more K+ ion stays intracellular giving the cell inside positive charge.