Microbiology Now: Microbial Hunter: Pseudomonas aeruginosa Senses and Scavenges

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Microbiology Now: Microbial Hunter: Pseudomonas aeruginosa Senses and Scavenges Nutrients from Damaged Tissues When Pseudomonas aeruginosa are exposed to damaged cells in the lungs of someone with cystic fibrosis, certain steps must occur to allow chemotaxis to occur. These steps have been most thoroughly studied in E. coW. What steps occur in response to a chemical to allow E. coli cells to move towards an attractant? Drag and drop each item into the correct sentence. You may use words more than once. View Available Hint(s) Reset Help CheA-P CheY-P CheW methyl-accepting chemotaxis is the coupling protein that associates with MCP is the sensor kinase that associates with MCP. protein CheY CheA associates with a sensor kinase and a coupling protein to trigger autophosphorylation. can bind to the flagellum in order to allow runs to occur undergoes autophosphorylation at a higher rate when the attractant concentration decreases. contributes a phosphate to which determines the direction of movement of the flagellum.

Explanation / Answer

CheW A coupling protein

cheA-a sensor kinase

CheY associates with sensory kinase and coupling protein to trigger autophosphorylation

CheY-P - it directly interacts with Fli on the flagellum and reverses rotation to CW, causing the cell to tumble the rate of autophosphorylation decreases

CheA-P contributes phosphate to cheY-P which determines the direction of movement of the flagellum

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