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Indicate whether each of the following descriptions better applies to COPI, COPI

ID: 211121 • Letter: I

Question

Indicate whether each of the following descriptions better applies to COPI, COPII or clathrin-coated vesicles.

They mediate transport from the ER to the cis Golgi network.

They are involved in retrograde transport in the Golgi.

They are involved in transporting mannose-6-phospate containing molecules to the correct loaction.

These form at the plasma membrane as part of the endocytic process.

COPII coated vesicles

COPI coated vesicles

clathrin-coated vesicles

      -       A.       B.       C.   

They mediate transport from the ER to the cis Golgi network.

      -       A.       B.       C.   

They are involved in retrograde transport in the Golgi.

      -       A.       B.       C.   

They are involved in transporting mannose-6-phospate containing molecules to the correct loaction.

      -       A.       B.       C.   

These form at the plasma membrane as part of the endocytic process.

A.

COPII coated vesicles

B.

COPI coated vesicles

C.

clathrin-coated vesicles

Explanation / Answer

COPII-coated vesicles mediate transport from ER to the cis Golgi network, because COPII-coated vesicles are capable of carrying its cargo along the secretory pathway to the Golgi apparatus. As the COPI-coated vesicles are capable of mediating retrograde transport from cis-Golgi back to the ER, the answer for this question will be B, which indicates COPI-coated vesicles. Clathrin-coated vesicles are involved in transporting mannose-6-phospate containing molecules to the correct location. Clathrin-coated vesicles form at the plasma membrane as part of the endocytic process, because the clathrin-coated vesicles are known to be capable of mediating endocytosis from the plasma membrane to endosomal compartments and the Golgi.