Hetcrozygus Hmozygous recessive? Q5) In a study of the Hopi, a Native American t
ID: 213420 • Letter: H
Question
Hetcrozygus Hmozygous recessive? Q5) In a study of the Hopi, a Native American tribe of central Arizona, Woolf and Dukepoo (1959) found 26 albino individuals in a total population of 6000. This form of albinism is controlled by a single gene with two alleles: albinism is recessive to normal skin coloration. a) Why can't you calculate the allele frequencies from this information alone? b) Calculate the expected allele frequencies and genotype freque s if the population were in Hardy-Weinberg equilibrium. How many of the Hopi are estimated to be carriers of the recessive albino allele? 06) Determine the allele frequencies for the following ideal populations where there are two alleles, and the upper-case letter is dominant to the lower case. a) A population in which is 9% of the individuals have the e' phenotype b) A population in which is 60% of the individuals have the A' phenotype 20Explanation / Answer
Answer:
5). a.
We can calculate the allele frequency by knowing recessive genotype frequency. So first we need to calculate recessive genotype frequency, recessive allele frequency and then dominant allele frequency.
b). Recessive genotype frequency q^2= 26/6000= 0.004
Recessive (albino) allele frequency= q= 0.063
As p+q=1
p=1-0.063=0.937
The frequency of normal allele=p= 0.937
The frequency homozygous normal=p^2= 0.937*0.937= 0.878
The frequency of heterozygous normal=2pq= 2*0.937*0.063=0.118
The number of carrier individuals= 0.118*6000=708
6).
a). Frequency of "e" phenotype= q^2=9%=0.09
The frequency of recessive allele=e=q=0.3
As p+q=1
p=1-0.3=0.7
The frequency of dominant allele=E=p= 0.7
b).
The frequency of dominant phenotype =AA=60%
It means that recessive phenotype frequency=aa=40%= 0.4
Recessive allele frequency=a=0.63
p+q=1
p=1-0.63=0.37
The frequency of dominant allele=A=0.37