Which of the following is NOT associated with canonical G-protein coupled recept
ID: 214036 • Letter: W
Question
Which of the following is NOT associated with canonical G-protein coupled receptor (GPCR) signaling? Ras monomeric GTPase gets activated O Replacement of GDP with GTP causes dissociation of the subunit from the subunits of a heterotrimeric G-protein Adenylyl cyclase is activated, causing an increase in production of cyclic AMP (CAMP) Second messengers are released leading to signal amplification. O The receptor becomes phosphorylated and gets inactivated through binding with an inhibitory MUt siri.Explanation / Answer
Option e is correct because receptor become dephosphorylated and get inactivated .conversion of GTP into GDP and hence the inactivation of g protein.