The figure below shows the pathway through which nitric oxide (NO) triggers smoo
ID: 214038 • Letter: T
Question
The figure below shows the pathway through which nitric oxide (NO) triggers smooth muscle relaxation in a blood-vessel wall. Which of the following situations would lead to relaxation of the smooth muscle cells in the absence of acetylcholine? activated nerve terminal acetylcholine NO bound to guanylyl cyclase arginine cyclic GMP GTP RAPID RELAXATION OF SMOOTH MUSCLE CELL NO RAPID DIFFUSION OF NO ACROSS MEMBRANES endothelial cell mooth muscle cell a smooth muscle cell that has a defect in guanylyl cyclase such that it cannot bind NO a muscle cell that has cyclic GMP phosphodiesterase constitutively active a muscle cell that has a defect in guanylyl cyclase such that it constitutively converts GTP to cyclic GMP O a drug that blocks an enzyme involved in the metabolic pathway from arginine to NOExplanation / Answer
muscle cell that has a defect in guanylyl cyclase such that it consitutively converts GTP to cyclic GMP.
In the absence of acetylcholine, the activation of guanylyl cyclase is carried out by nitric oxide which acts as a regulatory molecule.