Predict what would happen if you treated cells with Cytocholasin D when the conc
ID: 214086 • Letter: P
Question
Predict what would happen if you treated cells with Cytocholasin D when the concentration of Gactin is lower than the critical concentration for either end.
Answers:1. Microfilaments stop growing and eventually lose subunits off of the minus end only.
2. Microfilaments stop growing and lose subunits off of the plus end only.
3 Microfilaments stop growing and lose subunits off of both ends Only. 4. microtubules would be affected
I know that 3 is not the right answer. Only one answer is it 1,2,4. Please explain. Thank You.
Explanation / Answer
Option 2 is the correct answer.
Cytochalasin D depolymerizes actin filaments by binding to the (+) end of F-actin, where it blocks further addition of subunits. hence, if the cells are treated with Cytocholasin D when the concentration of G-actin is lower than the critical concentration for either end, microtubules stop growing and lose subunits off the plus end only.