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The normal polypeptide A+ contains 150 amino acids. The mutant polypeptide A - h

ID: 215663 • Letter: T

Question

The normal polypeptide A+ contains 150 amino acids. The mutant polypeptide A- has an additional 25 amino acids inserted between the two amino acids in positions 35 and 36 of the normal polypeptide, and contains a total of 175 amino acids. Which of the following mutations may account for this change in the structure of the resulting polypeptide?

A nonsense mutation

A sense mutation caused by a base substitution

Duplication of one of the introns of the gene

Duplication of one of the exons of the gene

A sense mutation caused by a base insertion in the last exon

A.

A nonsense mutation

B.

A sense mutation caused by a base substitution

C.

Duplication of one of the introns of the gene

D.

Duplication of one of the exons of the gene

E.

A sense mutation caused by a base insertion in the last exon

Explanation / Answer

Which of the following mutations may account for this change in the structure of the resulting polypeptide?

C) Duplication of one of the introns of the gene