Consider the following pedigree of a rare autosomal recessive disease. Assume al
ID: 21702 • Letter: C
Question
Consider the following pedigree of a rare autosomal recessive disease. Assume all people marrying into the pedigree do not carry the abnormal allele. If individuals A and B have a child, what is the probability that the child will have the disease? If individuals C and D have a child, what is the probability that the child will have the disease? If the first child of C * D is normal, what is the probability that their second child will have the disease? If the first child of C * D has the disease, what is the probability that their second child will have the disease?Explanation / Answer
a) A----WILL BE ----HETEROZYGOUS FOR RECESSIVE ALLELE-----NORMAL PHENOTYPE B--WILL BE ----HETEROZYGOUS FOR RECESSIVE ALLELE-----NORMAL PHENOTYPE Aa x Aa 25% will be affected ============ b)1/4 ------------------- c)1/4 ,every issue is Independent and new event c)1/4 ,every issue is Independent and new event