Paste 1. (2) How many actual QH: molecules, total (rather than net) are oxidized
ID: 217696 • Letter: P
Question
Paste 1. (2) How many actual QH: molecules, total (rather than net) are oxidized in the process of reducing 2 molecules of cytoch rome c? 2. (2) How many cytochrome c molecules are needed to fully reduce 1 molecule of 02? 3. (2) Oligomycin is an antibiotic that blocks proton transfer through the Fo proton channel of ATP synthase. What is the effect on (a) ATP synthesis? (b) electron transport? (e) oxygen consupmtion when oligomycin is added to a suspension of.cespiring mitochondria? (d) When dinitropbenal is added to the suspension in (c) above? 4. (2) A man presents in the emergency room after ingesting an insecticdide. The Poison Control Center indicates that the insecticide contains cyanide (CN), which binds to and completely inhibits cytochrome coxidase. Would ATP synthesis in this man's mitochondria be stopped? 5. (2) The compound bongkrekicadd (love the name) binds tightly to the ADP/ATP translocase, stopping it from working What does this do to: (a) electron transport? (b) ATP synthesis? Page 1 of 1 187 words English (US)Explanation / Answer
1) One moleclue of QH2 is necessary for reducing two Ccytochrome C molecules
2) to reduce one molecule of O2, 4 molecules of reduced Cytocrome C is required.
3) Oligomycin inhibits ATP synthesis.
Due to the inhibiton of ATP synthesis, there is a significant decrease in electron transport however not completely stopped.
Oxygen consumption stops in respiring mitochondria, as ATP synthesis and electron transport is reduced.
Dinitrophenol can shuttle protons (hydrogen cations) across a biological membranes. It dissipates the proton gradient across mitochondria and chloroplast membranes, collapsing the proton motive force that the cell uses to produce ATP, instead the energy of the proton gradient is lost as heat.?
4)Cyanide binds to and inhibs cytochrome C oxidase. This the fourth complex in the ETC. due to its inhibition, electron transport is distrupted and hence cells cannot produce ATP.
5) Bongkrekic acids inhibits the enzyme ATP/ADP translocase. Hence this chemical does not disrupt the process electron transport or ATP synthesis. However, as it inhibits the translocase enzyme, ATP is not translocatd out of the mitochondria and hence starves the cells of ATP.