Map Lehninger Principles of Biochemistry Nelson I Cox MHE/Freeman by Sepling Lea

Question

Map Lehninger Principles of Biochemistry Nelson I Cox MHE/Freeman by Sepling Learning Prostaglandins are a class of eicosanoids, fatty acid derivatives with a variety of extremely potent actions on vertebrate tissues. They are responsible for producing fever and inflammation and its associated pain Prostaglandins are derived from the 20-carbon fatty acid arachidonic acid in a reaction catalyzed by the enzyme prostaglandin endoperoxide synthase. This enzyme, a cyclooxygenase, uses oxygen to convert arachidonic acid to PGG2, the immediate precursor of many different prostaglandins (a) Rate of formmation The kinetic data given in the table are for the reaction catalyzed by a mutant of prostaglandin Arachidonic acid Rate of oaoof PGG2 endoperoxide synthase. Focusing here on the first two columns, determine the Vmx and Km of (mM) of PGGwith 10 mg/mL (mWmin) 8.33 9.60 12.9 17.6 25.9 the enzyme 0.310 0.372 0.558 0.930 2.17 13.3 15.0 18.9 24.0 31.1 Number m714 mM/ min Number K0.59 mM Incorrect. See lower panel for feedback Please scroll down

Explanation / Answer

Vmax should be 31.1 for this graps as it is the maximum rate.

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