Medical Genomics ED 4230 Human Genetics and Dr. Chun Xu B Population stratificat

Question

Medical Genomics ED 4230 Human Genetics and Dr. Chun Xu B Population stratification C. Genetic diversity D. Genetic drift E. ow Answer 12. Analysis of pairwise measurements of D' for neighboring variants via genome reveals a complex genetic architecture for LD, thus D' close to 1 is strong LD and close to 0 is weak LD A. True B. False 13. What property is associated with the co-inheritance of marker alleles (two loci are very close each other frequencies that deviate from that expected based on the allele frequencies? A. Marker association (B.) Linkage disequilibrium Recombination D. Marker phasing E. Marker coupling E gene in Populations and certain allele of the Apo E gene is predisposi 14.Genotype Frequencies of Apo Alzheimer disease Number of Observed subjectsGenotype Allele Derived Allele Genotypes Frequencies Frequency 0.821 0.168 0.011 1.00 647 134 E3/E3 E3/E4 E4/E47 Total ?? E4 788 What is allele frequency for heterozygous major allele? What is allele frequency for heterozygous minor allele? do you calculate (e.g., list formula) 10.17 for minor allele

Explanation / Answer

LD is linkage disequillibrium and the answer according to me should be True as D´ of 1.0 is high disequilibrium so D' of 0 should be weak.

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