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How is a naked linear DNA molecule condensed (packed) into heterochromatin and r

ID: 218842 • Letter: H

Question

How is a naked linear DNA molecule condensed (packed) into heterochromatin and relaxed (expanded) back into chromatin? a) chromatin remodeling complexes compact or relax naked DNA molecules b) naked DNA associates with histones (H2A, H2B, H3 and H4) to create highly compacted DNA structures (heterochromatin). naked DNA associates with histones forming nucleosomes (chromatin) and chemical modifications at histone tail domains (acetylation, methylation or phosphorylation) determine if chromatin remodeling complexes promote compaction (heterochromatin) or relaxation (chromatin) of DNA protein complexes d) histone H1 determines if a DNA region is to be compacted or retain its relaxed state.

Explanation / Answer

Answer: (c) naked DNA associates with histones forming nucleosomes (chromatin) and chemical modifications at histone tail domains (acetylation, methylation or phosphorylation) determine if chromatin remodeling complexes promote compaction (heterochromatin) or relaxation (chromatin) of DNA protein complexes.