I need help with this, the last questions that I posted had wrong answers Thank
ID: 225536 • Letter: I
Question
I need help with this, the last questions that I posted had wrong answers
Thank you
Part C
Use what you know about the bcl-2 family of genes (which includes the ced-9 gene in C. elegans) to predict the outcomes of the situations described below.
Drag the terms on the left to the appropriate blanks on the right to complete the sentences. Terms can be used once, more than once, or not at all
prevent
overexpression
low
high
promote
lack of expression
1. In C. elegans, of ced-9 during embryonic development leads to the survival of cells that would normally undergo apoptosis.
2. In humans, cells that express levels of bcl-2 are more susceptible to apoptosis.
3. In humans, cells that express levels of bcl-2 are less likely to undergo apoptosis.
4. In human cells, of bcl-2 is associated with uncontrolled cell growth that leads to a type of cancer called follicular lymphoma.
5. In human cell lines, scientists can manipulate the cells to force the expression of bcl-2 to apoptosis.
6. In humans with follicular lymphoma, a potential therapeutic would be to the expression of bcl-2 in the cancerous cells.
prevent
overexpression
low
high
promote
lack of expression
1. In C. elegans, of ced-9 during embryonic development leads to the survival of cells that would normally undergo apoptosis.
2. In humans, cells that express levels of bcl-2 are more susceptible to apoptosis.
3. In humans, cells that express levels of bcl-2 are less likely to undergo apoptosis.
4. In human cells, of bcl-2 is associated with uncontrolled cell growth that leads to a type of cancer called follicular lymphoma.
5. In human cell lines, scientists can manipulate the cells to force the expression of bcl-2 to apoptosis.
6. In humans with follicular lymphoma, a potential therapeutic would be to the expression of bcl-2 in the cancerous cells.
Explanation / Answer
1.In C. elegans, activation/high levels of ced-9 during embryonic development leads to the survival of cells that would normally undergo apoptosis.
2.In humans, cells that express low levels of bcl-2 are more susceptible to apoptosis.
3. In humans, cells that express high levels of bcl-2 are less likely to undergo apoptosis.
4.In human cells, over-expression of bcl-2 is associated with uncontrolled cell growth that leads to a type of cancer called follicular lymphoma.
5. In human cell lines, scientists can manipulate the cells to force the high expression of bcl-2 to prevent apoptosis.