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Which of the following statements about the oxidative decarboxylation of pyruvat

ID: 225647 • Letter: W

Question

Which of the following statements about the oxidative decarboxylation of pyruvate under aerobic conditions in animal cells is correct? The methyl group is eliminated as CO_2 The process is considered as the first catalytic step in the TCA cycle. One of the products of the reactions of the Pyruvate Dehydrogenase Complex is Acetyl-CoA. The Pyruvate Dehydrogenase Complex uses all of these as cofactors: NAD^+, lipoic acid, pyridioxal phosphate, and FAD. The reaction is so important to energy production that the E1 and E_2 components of Pyruvate Dehydrogenase can be used for the oxidative decarboxylation of a-ketoglutarate.

Explanation / Answer

The correct statements are:

The process is considered as the first catalytic step in the TCA cycle.

One of the products of the reaction of the Pyruvate Dehydrogenase Complex is Acetyl CoA.