Related Questions for Experiment 2 1. LDso is a measure of toxicity-lethal dose,
ID: 229091 • Letter: R
Question
Related Questions for Experiment 2 1. LDso is a measure of toxicity-lethal dose, 50 percent kill. LDso is the dose in mg of the substance which is most likely to cause death within 14 days in one half of the animals used in the testing per kilogram of body weight. The LD so of barium chloride is 118 mg/kg and the LDso of strontium chloride is estimated at 2060 mg/kg. Which compound is more toxic? 2. Barium compounds are chemically very similar to strontium compounds. Water-soluble compounds of both are toxic, but to different degrees. An antidote for barium chloride poisoning is to orally administer 30 grams of sodium sulfate in 250 mL of water. Explain the chemical basis for this antidote.Explanation / Answer
1) The Lower the LD (Leathal Dose) value the more toxic is the chemical compoud.The Barium chloride is more toxic than the strontium chloride as it has lower LD value . The LD value indicate the amount of substance needed to kill the person, so lower the LD value more is its power or effect to kill the person with small amount.
2) Sodium Sulphate is used as antidote for Barium Chloride. Both are soluble in water and forms the ions Na+,SO42-,Ba2+ and Cl-. A Double Decomposition reactions occurs forming Barium Sulphate and Sodium chloride. The Barium sulphate is insoluble white precipitate (it has low solubility) and sodium chloride remain in solution which is not harmful. The barium which causes the toxicity is precipitated as Barium sulphate immediately when give Sodium Sulphate. So it is right choice to use Sodium Sulphate as antidote in Barium Chloride poisoning beacause it readily precipitates the solube Barium chloride decreasing toxicity.