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16. The maternal copy of chromosome 19 has undergone an inversion such that its

ID: 261412 • Letter: 1

Question

16. The maternal copy of chromosome 19 has undergone an inversion such that its new ordering is as follows:

A-*-B-E-D-C-F(* denotes the centromere).

The normal ordering of the paternal copy is as follows:

a-*-b-c-d-e-f.

According to the location of the affect chromosome region with respect to the centromere, how would this inversion be classified?

17. Assume the crossing over occurs between d and e during meiosis. Denote all possible monads in the gametes using the asterisk and upper and lower-case letters as above.

18. Gametes containing which of the above monads would NOT be expected to be viable?

Explanation / Answer

3. Non-viability is only when a important gene which is essential for survival (ex. House-keeping genes) is missing. Since in the above crossover deletion of any gene is not occuring and hence, all the monads will be viable.