Please answer the following questions. 1. Phospholipids are constructed from 1,2
ID: 268797 • Letter: P
Question
Please answer the following questions.
1. Phospholipids are constructed from 1,2-diacylglycerol and a polar head group using two similar strategies. What molecule provides the phosphate group for many of these phospholipids? A. ATP B. acyl phosphates C. CTP D. phosphatidic acid E. glycerol 3-phosphate 2. Cellular uptake of LDL by the LDLR results in which homeostatic mechanism? A. binding of LDL-derived cholesterol by sterol cleavage activated protein (SCAP) B. release of sterol response element binding protein 2 (SREBP2) directly to the lysosome C. upregulation of expression of genes like ABCA1 and stearoyl-CoA desaturase 1 (SCD1) D. recycling and synthesis of new LDLR proteins expressed at the plasma membrane E. upregulation of the rate-limiting enzyme of cholesterol synthesis 3-hydroxymethyl-glutarylCoAreductase 3. Telomeres are noncoding sequences on the ends of chromosomes. They contain a high concentration of guanosine. Given this information, what other structure may be in telomeres? A. cyclobutane dimers B. a high concentration of triplexes C. cruciform D. tetraplexes E. A-form DNA 4. Why are two different restriction endonucleases used in DNA recombination? A. to permit proper orientation of the DNA insert into the plasmicd B. to cut both phosphodiester bonds and hydrogen bonds C. One is required to produce the open plasmid, and the other produces the insert. D. Each is specific for a sequence found on one of the two strands of DNA. E. One is specific for purines, and one is specific for pyrimidines S. What method requires polymerase chain reaction A. microarray B. RFLP DNA fingerprinting C. two-dimensional gel electrophoresis D. yeast two-hybrid analysis E. use of a restriction modification systemExplanation / Answer
1. Glycerol 3-phosphate
2. B. Release of sterol response element binding protein 2 directly by lysosome
3. A. Cyclobutane dimers
4. C. One is required to produce the open plasmid, the other produce the insert
5. Microarray