Please explain why as well! 7. Which of the following statement(s) about 2,4-din
ID: 271686 • Letter: P
Question
Please explain why as well!
7. Which of the following statement(s) about 2,4-dinitrophenol (DNP) is/are TRUE?
A. It is a hydrophobic compound
B. It uncouples electron transport from ATP synthesis
C. It diffuses through the inner mitochondrial membrane
D. It binds to protons
E. All of the above
8. Which of the following inhibitor(s), when used on isolated mitochondria, is/are likely to maintain/keep complex III in an oxidized state?
A. Rotenone
B. Cyanide
C. Azide
D. Carbon monoxide
E. A & B
F. A & C
G. B & D
H. C & D
9.A mutation in complex II would be expected to impair electron transport from which compound below?
A. Alpha-ketoglutarate
B. Succinate
C. Malate
D. Isocitrate
E. Acetyl-CoA
10. From the list below, choose the ONE site or step along the ETC that is not coupled to ATP synthesis.
A. Succinate to Coenzyme Q
B. NADH to Coenzyme Q
C. Coenzyme Q to Cytochrome C
D. Cytochrome C to O2
11. How does oligomycin work?
A. It is an uncoupler of oxidative phosphorylation
B. It inhibits NADH dehydrogenase
C. It blocks the flow of protons through F0
D. It is an inhibitor of cytochrome oxidase
Explanation / Answer
Answer=
7. Which of the following statement(s) about 2,4-dinitrophenol (DNP) is/are TRUE?
E. All of the above
Explaination- 2,4 -dinitrophenol is
A. It is a hydrophobic compound
B. It uncouples electron transport from ATP synthesis - It is uncoupler that uncouples the phosphorylation i.e. ATP formation from electron transport.
C. It diffuses through the inner mitochondrial membrane -it carries the protons across the inner mitochondria membrane.
D. It binds to protons