Please show work and answer questions 2 and 3 with provided information from Gen
ID: 271802 • Letter: P
Question
Please show work and answer questions 2 and 3 with provided information from Genotypes and question 1... THANK YOU!!
Genotypes:
A1/A1: 80
A1/A2: 20
A2/A2: 90
Total: 190
1. Use the data above to estimate the frequency of the two alleles. Be sure it is clear which frequency corresponds to which allele.
It is given that, the frequency of A1A1 or p2 is = 80/190 or 0.421
The frequency of A1A2 or 2pq is = 20/190 = 0.105
The frequency of A2A2 or 2pq is = 90/190 = 0.473
The frequency of A1 allele or p is = Frequency of p2 + ½ (2pq) = 0.421 + ½ (0.105) = 0.4735
The frequency of A2 allele or q is = Frequency of q2 + ½ (2pq) = 0.473 + ½ (0.105) = 0.525
2. Use your answers from question 1 to calculate the EXPECTED FREQUENCY for each of the three genotypes
3. Use your answers from question 2 to calculate the EXPECTED NUMBER for each of the three genotypes
Explanation / Answer
Find the below image for answer and explanation...
1. Allele frequency estimation
Genotype
Freequency
Allele A1
Allele A2
Total
A1 A1
80
160
0
160
A1 A2
20
20
20
40
A2 A2
90
0
180
180
Total
190
180
200
380
Allele A1
= 180/380
0.47
Allele A2
= 200/380
0.53
2. Expected frequency estimation:
A1 A1
= 0.47*0.47 = 0.224
A1 A2
= 2*0.47*0.53= 0.499
A2 A2
= 0.53*0.53 = 0.277
3. Expected number estimation
A1 A1
= 0.47*0.47 = 0.224 * 190
= 43
A1 A2
= 2*0.47*0.53= 0.499* 190
= 95
A2 A2
= 0.53*0.53 = 0.277*190
= 53
Genotype
Freequency
Allele A1
Allele A2
Total
A1 A1
80
160
0
160
A1 A2
20
20
20
40
A2 A2
90
0
180
180
Total
190
180
200
380