1. During _____________________ [name stage of replication], hemagglutinin prote
ID: 274628 • Letter: 1
Question
1. During _____________________ [name stage of replication], hemagglutinin
proteins binds sialic acid molecules on the __________________ [name specific
structure of host cell] of the respiratory cell.
2. During penetration and __________________ [name stage of replication], the virion
enters the cell by ______________________________ [name cellular process]
and is released into the cytoplasm of the cell following the fusion of the viral membrane with
the __________________ membrane; the capsid is subsequently removed.
3. During biosynthesis, the eight __________________ [positive or negative] – strand
_________ [DNA or RNA] genome segments enter the __________________
[name host cell structure] where the genome is replicated using the viral enzyme
________________________ [name specific enzyme]. This activity will produce
genome copies and __________________ [name macromolecule] that will be
translated to produce viral structural proteins.
4. During assembly, viral surface proteins that were exported to the ________________
[name host cell structure] aggregate with other viral proteins and genome copies.
5. During __________________ [name stage of replication], infectious virions are
released from the host cell by the process of __________________ [name process],
acquiring its __________________ [name viral structural component] from the host
cell as it leaves.
Explanation / Answer
1. During adsorption stage , hemeagglutinin protein binds to the sialic acid molecules on the epithellium of the respiratory cell.
2. During penetration and host cell entry , the virion enters the cell through endocytosis.
3. During biosynthesis , the eight segments of - strand RNA genome enter the cytoplasm of the host cell membrane where the genome is replicated using viral enzyme Replicase . This activity will produce genome copies and mRNA that will be translated to produce viral proteins.
4. During assembly , the viral surface proteins are exported to the cell surface , aggregate with other viral proteins and genome copies .
5. During release stage infectious virions are released from the host cell by the process of exocytosis acquiring its nucleocapsid structure from the host cell as it leaves.